About The Study
Study location: Plant City, FL
Escherichia coli (E. Coli) is a type of bacteria that normally lives in the intestines of healthy people and animals. Most types of E. coli are harmless but there are some strains that can cause more severe symptoms such as diarrhea, vomiting, stomach pain or cramping, and urinary tract infections (UTIs). E. coli can affect anyone who is exposed to the bacteria, but older adults are at higher risk of experiencing more serious complications from the infection. Exposure to E. coli bacteria most commonly comes from contaminated water or food, or personal contact.
Researchers are looking for adults aged 60 and older with a history of urinary tract infection (UTI) in the past 2 years. The study will investigate the efficacy of an investigational vaccine compared to placebo in the prevention of E. coli disease.
Study Criteria
To qualify, participants must:
- Be at least 60 years of age
- Have a history of urinary tract infection (UTI) in the past 2 years
- Feel comfortable, or have a caregiver who is comfortable, using an application on a smartphone
Why Participate?
There is no cost to participate and health insurance is not required to participate. Eligible participants will receive the investigational vaccine or placebo and some study-required medical care at no cost.